Effect of two interventions on reducing antibiotic prescription in pharyngitis in primary care.

نویسندگان

  • Carl Llor
  • Josep María Cots
  • Beatriz González López-Valcárcel
  • Juan de Dios Alcántara
  • Guillermo García
  • Javier Arranz
  • María José Monedero
  • Jesús Ortega
  • Vicenta Pineda
  • Gloria Guerra
  • Manuel Gómez
  • Silvia Hernández
  • José Paredes
  • Marina Cid
  • Carolina Pérez
چکیده

OBJECTIVES to evaluate the effect of two interventions on reducing antibiotic prescription in pharyngitis. METHODS a prospective, non-randomized, before-after controlled study was carried out in primary care centres throughout Spain. General practitioners (GPs) registered all cases of pharyngitis during a 3 week period before and after two types of intervention in 2008 and 2009, respectively. Full intervention consisted of discussion sessions of the results of the first registry, courses for GPs, guidelines, patient information leaflets, workshops on rapid tests and the use of rapid antigen detection tests (RADTs) in their consulting offices. The physicians in the partial intervention group underwent all the above intervention except for the workshop, and RADTs were not provided. A control group was also included in 2009. Multilevel logistic regression was performed considering the prescription of antibiotics as the dependent variable. RESULTS a total of 280 GPs registered cases with pharyngitis (70 partial intervention and 210 full intervention). Fifty-nine new physicians were included as a control group. A total of 6849 episodes of pharyngitis were registered. Antibiotic prescription was significantly lower after intervention for the full intervention group, but not for the partial intervention group. According to the multivariate model, in comparison with the control group, the odds ratio of antibiotic prescription after the intervention was 0.52 [95% confidence interval (95% CI) 0.23-1.18] in the partial intervention group and 0.23 (95% CI 0.11-0.47) in the full intervention group. CONCLUSIONS intervention was beneficial for reducing the prescription of antibiotics, but was only statistically significant when the GPs were provided with RADTs.

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عنوان ژورنال:
  • The Journal of antimicrobial chemotherapy

دوره 66 1  شماره 

صفحات  -

تاریخ انتشار 2011